Designing Women (1986–91)
Smart played Charlene Frazier, the sweet-as-pie but not-so-sharp office manager at Sugarbaker’s Atlanta design firm.
Frasier (2000–01)
She won her first Emmy for her recurring guest role as Frasier’s former classmate crush turned girlfriend, Lana Gardner.
Kim Possible (2002–07)
In her most “animated” role, Smart was the voice of Dr. Ann Possible, the cartoon neurosurgeon mother of teen crime-stopper Kim Possible.
24 (2006–07)
Her role as the powerful yet impulsive first lady Martha Logan on the hit KieferSutherland drama earned her back-to-back Emmy nominations.
Samantha Who? (2007–09)
In another Emmy-winning TV performance, she was Regina Newly, the narcissistic mother of an amnesiac (ChristinaApplegate) who learns the hard truth about her “former” life.
Fargo (2015)
Smart steals the spotlight in this black comedy TV spinoff of the hit film as the head of a North Dakota crime family.
Legion (2017–18)
The Marvel X-Men series featured Smart as Melanie Bird, the boss of the facility that houses super-powered mutants.
Watchmen (2019)
Playing agent Laurie Blake in this limited HBO series based on the DC Comics graphic novel, Smart’s former superhero character now hunts down other superheroes herself.
Mare of Easttown (2021)
The lauded limited streaming series presented Smart with the prime role of Helen Fahey, who spars with her small-town Pennsylvania detective daughter (KateWinslet).
Hacks (2021– )
She packs in the punchlines as stand-up comic Deborah Vance, who tries to revitalize her fleeting fame with the help of a young female TV writer.